{"id":2034,"date":"2016-04-17T22:06:02","date_gmt":"2016-04-17T12:06:02","guid":{"rendered":"https:\/\/theveterinarian.com.au\/?p=2034"},"modified":"2016-04-14T22:21:42","modified_gmt":"2016-04-14T12:21:42","slug":"abstracts-canine-oral-mucosal-mast-cell-tumours","status":"publish","type":"post","link":"https:\/\/theveterinarian.com.au\/?p=2034","title":{"rendered":"Abstracts: Canine oral mucosal mast cell tumours"},"content":{"rendered":"Mast cell tumours (MCTs) are the most common cutaneous tumours of dogs, however rarely they can arise from the oral mucosa. This subset of MCT is reported to demonstrate a more aggressive clinical course than those tumours on the haired skin and the authors hypothesised that dogs with oral, mucosal MCT would have a high incidence of local lymph node metastasis at presentation and that this would be a negative prognostic factor. An additional hypothesis was that mitotic index (MI) would be prognostic. <!--more-->\r\n\r\nThis retrospective study examines 33 dogs with MCTs arising from the oral mucosa. The results suggest that oral mucosal MCTs in the dog have a high incidence of lymph node metastasis at diagnosis (55 per cent) which results in a poor prognosis. MI and nodal metastasis is highly prognostic. Loco-regional progression is common in these patients and dogs with adequate local control of their tumour had an improved outcome. Despite a more aggressive clinical course, treatment can result in protracted survivals, even when metastasis is present.\r\n\r\nThe study is from the Department of Veterinary Clinical Science, Liverpool University, Liverpool, UK; Small Animal Teaching Hospital, Liverpool University, Liverpool, UK; Oncology Unit, Animal Health Trust, Newmarket, UK; CSAS, Animal Health Trust, Newmarket, UK, and Small Animal Hospital, University of Glasgow, Glasgow, UK.\r\n\r\nElliott JW, Cripps P, Blackwood L, et al. <em>Veterinary and Comparative Oncology<\/em> 2016; 14 (1): 101-111; doi: 10.1111\/vco.12071","protected":false},"excerpt":{"rendered":"<p>Mast cell tumours (MCTs) are the most common cutaneous tumours of dogs, however rarely they can arise from the oral mucosa. This subset of MCT is reported to demonstrate a more aggressive clinical course than those tumours on the haired skin and the authors hypothesised that dogs with oral, mucosal MCT would have a high [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[54,149,1704,1703,1705,55,653],"class_list":["post-2034","post","type-post","status-publish","format-standard","hentry","category-abstracts","tag-abstracts-2","tag-canines","tag-lumph-nodes","tag-mast-cell-tumours","tag-metastasis","tag-research","tag-university-of-glasgow"],"rise-blocks_total_comments":0,"rise-blocks_categories":[{"term_id":3,"name":"Abstracts","slug":"abstracts","term_group":0,"term_taxonomy_id":3,"taxonomy":"category","description":"","parent":0,"count":237,"filter":"raw","cat_ID":3,"category_count":237,"category_description":"","cat_name":"Abstracts","category_nicename":"abstracts","category_parent":0}],"rise-blocks_excerpt":"Mast cell tumours (MCTs) are the most common cutaneous tumours of dogs, however rarely they can arise from the oral mucosa. This subset of MCT is reported to demonstrate a more aggressive clinical course than those tumours on the haired skin and the authors hypothesised that dogs with oral, mucosal MCT would have a high incidence of local lymph node..","blog_post_layout_featured_media_urls":{"thumbnail":"","full":""},"categories_names":{"3":{"name":"Abstracts","link":"https:\/\/theveterinarian.com.au\/?cat=3"}},"tags_names":{"54":{"name":"abstracts","link":"https:\/\/theveterinarian.com.au\/?tag=abstracts-2"},"149":{"name":"canines","link":"https:\/\/theveterinarian.com.au\/?tag=canines"},"1704":{"name":"lumph nodes","link":"https:\/\/theveterinarian.com.au\/?tag=lumph-nodes"},"1703":{"name":"mast cell tumours","link":"https:\/\/theveterinarian.com.au\/?tag=mast-cell-tumours"},"1705":{"name":"metastasis","link":"https:\/\/theveterinarian.com.au\/?tag=metastasis"},"55":{"name":"research","link":"https:\/\/theveterinarian.com.au\/?tag=research"},"653":{"name":"University of Glasgow","link":"https:\/\/theveterinarian.com.au\/?tag=university-of-glasgow"}},"comments_number":"0","wpmagazine_modules_lite_featured_media_urls":{"thumbnail":"","cvmm-medium":"","cvmm-medium-plus":"","cvmm-portrait":"","cvmm-medium-square":"","cvmm-large":"","cvmm-small":"","full":""},"_links":{"self":[{"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/posts\/2034","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2034"}],"version-history":[{"count":1,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/posts\/2034\/revisions"}],"predecessor-version":[{"id":2039,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/posts\/2034\/revisions\/2039"}],"wp:attachment":[{"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2034"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2034"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2034"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}