{"id":2789,"date":"2021-07-13T16:33:05","date_gmt":"2021-07-13T06:33:05","guid":{"rendered":"https:\/\/theveterinarian.com.au\/?p=2789"},"modified":"2021-07-09T16:37:36","modified_gmt":"2021-07-09T06:37:36","slug":"abstracts-interferon-therapies-in-small-animals","status":"publish","type":"post","link":"https:\/\/theveterinarian.com.au\/?p=2789","title":{"rendered":"Abstracts: Interferon therapies in small animals"},"content":{"rendered":"\n<p>Interferons (IFNs) are cytokines that play an important role in the immune response of animals and humans. A number of studies reviewed here have evaluated the use of human, canine and feline IFNs as treatments for infectious, inflammatory and neoplastic disease in dogs and cats. <\/p>\n\n\n\n<p>Recombinant canine IFN-\u03b3 is deemed an efficacious therapy for canine atopic dermatitis. Recombinant feline IFN-\u03c9 is effective against canine parvoviral enteritis and has also been recommended for canine atopic dermatitis. <\/p>\n\n\n\n<!--more-->\n\n\n\n<p>Based on limited evidence, recombinant canine IFN-\u03b1 could be a topical treatment option for dogs with gingivitis and keratoconjunctivitis sicca. Conclusive evidence is lacking for other diseases and large randomised controlled trials are needed before IFNs can be recommended for other indications.<\/p>\n\n\n\n<p><strong>Keywords:&nbsp;<\/strong>Cat; Dog; IFN-\u03b1; IFN-\u03b3; IFN-\u03c9.<\/p>\n\n\n\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Mueller+RS&amp;cauthor_id=33840487\">Ralf S Mueller<\/a><sup>&nbsp;<\/sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33840487\/#affiliation-1\"><sup>1<\/sup><\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Hartmann+K&amp;cauthor_id=33840487\">Katrin Hartmann<\/a><sup>&nbsp;<\/sup><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33840487\/#affiliation-2\"><sup>2<\/sup><\/a><sup><\/sup><\/p>\n\n\n\n<p>Vet J.\u00a02021 May;271:105648.doi: <a href=\"http:\/\/doi.org\/10.1016\/j.tvjl.2021.105648\">10.1016\/j.tvjl.2021.105648<\/a>.\u00a0<\/p>\n\n\n\n<p><sup>1<\/sup>Center for Clinical Veterinary\nMedicine, LMU Munich, Veterinaerstr. 13, 80539 Munich, Germany. Electronic\naddress: R.Mueller@lmu.de.<\/p>\n\n\n\n<p><sup>2<\/sup>Center for Clinical Veterinary\nMedicine, LMU Munich, Veterinaerstr. 13, 80539 Munich, Germany.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Interferons (IFNs) are cytokines that play an important role in the immune response of animals and humans. A number of studies reviewed here have evaluated the use of human, canine and feline IFNs as treatments for infectious, inflammatory and neoplastic disease in dogs and cats. Recombinant canine IFN-\u03b3 is deemed an efficacious therapy for canine [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[54,2187,55,2186],"class_list":["post-2789","post","type-post","status-publish","format-standard","hentry","category-abstracts","tag-abstracts-2","tag-interferon-therapies","tag-research","tag-small-animals"],"rise-blocks_total_comments":0,"rise-blocks_categories":[{"term_id":3,"name":"Abstracts","slug":"abstracts","term_group":0,"term_taxonomy_id":3,"taxonomy":"category","description":"","parent":0,"count":237,"filter":"raw","cat_ID":3,"category_count":237,"category_description":"","cat_name":"Abstracts","category_nicename":"abstracts","category_parent":0}],"rise-blocks_excerpt":"Interferons (IFNs) are cytokines that play an important role in the immune response of animals and humans. A number of studies reviewed here have evaluated the use of human, canine and feline IFNs as treatments for infectious, inflammatory and neoplastic disease in dogs and cats. Recombinant canine IFN-\u03b3 is deemed an efficacious therapy for canine atopic dermatitis. Recombinant feline IFN-\u03c9..","blog_post_layout_featured_media_urls":{"thumbnail":"","full":""},"categories_names":{"3":{"name":"Abstracts","link":"https:\/\/theveterinarian.com.au\/?cat=3"}},"tags_names":{"54":{"name":"abstracts","link":"https:\/\/theveterinarian.com.au\/?tag=abstracts-2"},"2187":{"name":"interferon therapies","link":"https:\/\/theveterinarian.com.au\/?tag=interferon-therapies"},"55":{"name":"research","link":"https:\/\/theveterinarian.com.au\/?tag=research"},"2186":{"name":"small animals","link":"https:\/\/theveterinarian.com.au\/?tag=small-animals"}},"comments_number":"0","wpmagazine_modules_lite_featured_media_urls":{"thumbnail":"","cvmm-medium":"","cvmm-medium-plus":"","cvmm-portrait":"","cvmm-medium-square":"","cvmm-large":"","cvmm-small":"","full":""},"_links":{"self":[{"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/posts\/2789","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2789"}],"version-history":[{"count":1,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/posts\/2789\/revisions"}],"predecessor-version":[{"id":2790,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/posts\/2789\/revisions\/2790"}],"wp:attachment":[{"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2789"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2789"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2789"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}