{"id":3275,"date":"2023-09-15T12:31:28","date_gmt":"2023-09-15T02:31:28","guid":{"rendered":"https:\/\/theveterinarian.com.au\/?p=3275"},"modified":"2023-09-12T12:36:09","modified_gmt":"2023-09-12T02:36:09","slug":"uqs-experimental-canine-cancer-vaccine-test","status":"publish","type":"post","link":"https:\/\/theveterinarian.com.au\/?p=3275","title":{"rendered":"UQ\u2019s experimental canine cancer vaccine test<\/strong>"},"content":{"rendered":"\n

University of Queensland veterinary researchers are recruiting pet dogs diagnosed with cancer to test an experimental vaccine.<\/p>\n\n\n\n

The clinical research trial is for dogs recently diagnosed with canine appendicular osteosarcoma, a common bone tumour that affects 10,000 dogs a year globally.<\/p>\n\n\n\n

Abhilasha Dadhich from UQ\u2019s School of Veterinary Science said researchers will assess two vaccine formulations.<\/p>\n\n\n\n

\u201cThese treatments aim to stimulate a dog\u2019s immune system to fight the spread of cancerous cells to other tissues of the body,\u201d Dadhich said.<\/p>\n\n\n\n

\u201cWe\u2019re essentially \u2018waking up\u2019 the dog\u2019s immune system to fight the cancer.<\/p>\n\n\n\n

\u201cThis has real potential to enhance the life expectancy of the pets in the trial.\u201d<\/p>\n\n\n\n

To be eligible, dogs need to have been diagnosed with appendicular osteosarcoma of long bones of the limbs with no evidence of metastasis, or cancer spread, based on a physical exam and radiographs.<\/p>\n\n\n\n

Dogs can be any breed but must be proceeding to surgery to treat their cancer.<\/p>\n\n\n\n

\u201cIf the dog meets these parameters, their owner will simply need to sign an informed consent document after the trial has been explained,\u201d Dadhich said.<\/p>\n\n\n\n

\u201cThe veterinary clinic will then collect blood and cancerous bone tissue from the dog at the time of surgery.<\/p>\n\n\n\n

\u201cOur prepared treatment is provided for free, administered to the dog in two doses.<\/p>\n\n\n\n

\u201cThe first vaccine dose will be given within two weeks of their surgery and the second dose as a booster three weeks later.<\/p>\n\n\n\n

\u201cFurther blood samples from the dog will be collected to assess its immune response.\u201d<\/p>\n\n\n\n

Professor Rachel Allavena, who is leading the team conducting the trial, said it was hoped immune treatments would one day be a straightforward process for veterinarians around the world.<\/p>\n\n\n\n

\u201cThis technique has incredible potential to reduce suffering in our pets and eventually a variation may even be able to help humans,\u201d Allavena said.<\/p>\n\n\n\n

\u201cWe\u2019re very eager to kick off this trial, as we have promising results from prior trials for dogs with cancer.\u201d<\/p>\n\n\n\n

Pet owners able to take their dog to the UQ VETS Small Animal Hospital at Gatton for surgery and treatment will be preferentially selected, however the team would also like to recruit patients from elsewhere in Australia, except NSW (due to an ethics requirement).<\/p>\n\n\n\n

The project team includes experienced veterinarians, board-certified pathologists and clinical trial experts who will provide regular monitoring and follow ups.<\/p>\n\n\n\n

Applications for the trial can be made at survey.app.uq.edu.au\/79E20EFE-DE3A-4652-8937-F992FA11EAE7 or questions can be directed to Dadhich at a.dadhich@uq.edu.au.<\/em><\/p>\n\n\n\n

Pic cap: Barney, owned by Professor Allavena, was given an early version of the vaccine when diagnosed with an aggressive bone cancer and 10 months later is alive and well<\/p>\n","protected":false},"excerpt":{"rendered":"

University of Queensland veterinary researchers are recruiting pet dogs diagnosed with cancer to test an experimental vaccine. The clinical research trial is for dogs recently diagnosed with canine appendicular osteosarcoma, a common bone tumour that affects 10,000 dogs a year globally. Abhilasha Dadhich from UQ\u2019s School of Veterinary Science said researchers will assess two vaccine formulations. \u201cThese treatments […]<\/p>\n","protected":false},"author":1,"featured_media":3276,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2545,2543,2548,2544,2546,2547,2550,2549,2542],"class_list":["post-3275","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","tag-appendicular-osteosarcoma","tag-canine-cancer","tag-clinical-research-trial","tag-experimental-vaccine","tag-immune-system-stimulation","tag-pet-health","tag-pet-owner-consent","tag-uq-vets-small-animal-hospital","tag-veterinary-research"],"rise-blocks_total_comments":0,"rise-blocks_categories":[{"term_id":1,"name":"Uncategorized","slug":"uncategorized","term_group":0,"term_taxonomy_id":1,"taxonomy":"category","description":"","parent":0,"count":12,"filter":"raw","cat_ID":1,"category_count":12,"category_description":"","cat_name":"Uncategorized","category_nicename":"uncategorized","category_parent":0}],"rise-blocks_excerpt":"University of Queensland veterinary researchers are recruiting pet dogs diagnosed with cancer to test an experimental vaccine. The clinical research trial is for dogs recently diagnosed with canine appendicular osteosarcoma, a common bone tumour that affects 10,000 dogs a year globally. Abhilasha Dadhich from UQ\u2019s School of Veterinary Science said researchers will assess two vaccine formulations. \u201cThese treatments aim to stimulate a dog\u2019s..","blog_post_layout_featured_media_urls":{"thumbnail":["https:\/\/theveterinarian.com.au\/wp-content\/uploads\/2023\/09\/UQ-Cancer-dog-150x150.png",150,150,true],"full":["https:\/\/theveterinarian.com.au\/wp-content\/uploads\/2023\/09\/UQ-Cancer-dog.png",416,255,false]},"categories_names":{"1":{"name":"Uncategorized","link":"https:\/\/theveterinarian.com.au\/?cat=1"}},"tags_names":{"2545":{"name":"Appendicular Osteosarcoma","link":"https:\/\/theveterinarian.com.au\/?tag=appendicular-osteosarcoma"},"2543":{"name":"Canine Cancer","link":"https:\/\/theveterinarian.com.au\/?tag=canine-cancer"},"2548":{"name":"Clinical Research Trial","link":"https:\/\/theveterinarian.com.au\/?tag=clinical-research-trial"},"2544":{"name":"Experimental Vaccine","link":"https:\/\/theveterinarian.com.au\/?tag=experimental-vaccine"},"2546":{"name":"Immune System Stimulation","link":"https:\/\/theveterinarian.com.au\/?tag=immune-system-stimulation"},"2547":{"name":"Pet Health","link":"https:\/\/theveterinarian.com.au\/?tag=pet-health"},"2550":{"name":"Pet Owner Consent","link":"https:\/\/theveterinarian.com.au\/?tag=pet-owner-consent"},"2549":{"name":"UQ VETS Small Animal Hospital","link":"https:\/\/theveterinarian.com.au\/?tag=uq-vets-small-animal-hospital"},"2542":{"name":"Veterinary Research","link":"https:\/\/theveterinarian.com.au\/?tag=veterinary-research"}},"comments_number":"0","wpmagazine_modules_lite_featured_media_urls":{"thumbnail":["https:\/\/theveterinarian.com.au\/wp-content\/uploads\/2023\/09\/UQ-Cancer-dog-150x150.png",150,150,true],"cvmm-medium":["https:\/\/theveterinarian.com.au\/wp-content\/uploads\/2023\/09\/UQ-Cancer-dog.png",300,184,false],"cvmm-medium-plus":["https:\/\/theveterinarian.com.au\/wp-content\/uploads\/2023\/09\/UQ-Cancer-dog.png",305,187,false],"cvmm-portrait":["https:\/\/theveterinarian.com.au\/wp-content\/uploads\/2023\/09\/UQ-Cancer-dog.png",400,245,false],"cvmm-medium-square":["https:\/\/theveterinarian.com.au\/wp-content\/uploads\/2023\/09\/UQ-Cancer-dog.png",416,255,false],"cvmm-large":["https:\/\/theveterinarian.com.au\/wp-content\/uploads\/2023\/09\/UQ-Cancer-dog.png",416,255,false],"cvmm-small":["https:\/\/theveterinarian.com.au\/wp-content\/uploads\/2023\/09\/UQ-Cancer-dog.png",130,80,false],"full":["https:\/\/theveterinarian.com.au\/wp-content\/uploads\/2023\/09\/UQ-Cancer-dog.png",416,255,false]},"_links":{"self":[{"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/posts\/3275","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3275"}],"version-history":[{"count":1,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/posts\/3275\/revisions"}],"predecessor-version":[{"id":3277,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/posts\/3275\/revisions\/3277"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=\/wp\/v2\/media\/3276"}],"wp:attachment":[{"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3275"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3275"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/theveterinarian.com.au\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3275"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}