In recent years there has been increased attention to the proposed entity of feline temporal lobe epilepsy (TLE).
Epileptic discharges in certain parts of the temporal lobe elicit very similar semiology, which justifies grouping these epilepsies under one name. Furthermore, feline TLE patients tend to have histopathological changes within the temporal lobe, usually in the hippocampus.
The initial aetiology is likely to be different but may result in hippocampal necrosis and later hippocampal sclerosis.
The aim of this article was not only to summarise the clinical features and the possible aetiology, but also being work to place TLE within the veterinary epilepsy classification.
Epilepsies in cats, similar to dogs, are classified based on the aetiology into idiopathic epilepsy, structural epilepsy and unknown cause. TLE seems to be outside of this classification, as it is not an aetiologic category, but a syndrome, associated with a topographic affiliation to a certain anatomical brain structure.
Magnetic resonance imaging, histopathologic aspects and current medical therapeutic considerations will be summarised, and emerging surgical options are discussed.
Akos Pakozdy 1, Peter Halasz 2, Andrea Klang 3, Borbala A Lörincz4, Martin J Schmidt 5, Ursula Glantschnigg-Eisl 6, Sophie Binks 7
Vet J. 2023 Jan; 291:105941. doi: 10.1016/j.tvjl.2022.105941.
1University Clinic for Small Animals, University of Veterinary Medicine, Vienna, Austria. Electronic address: akos.pakozdy@vetmeduni.ac.at.
2Institute of Experimental Medicine, Budapest, Hungary.
3Institute of Pathology, University of Veterinary Medicine, Austria.
4Clinic of Diagnostic Imaging, University of Veterinary Medicine Vienna, Austria.
5Department of Veterinary Clinical Sciences, Small Animal Clinic-Neurosurgery, Neuroradiology and Clinical Neurology, Justus-Liebig-University, Germany.
6University Clinic for Small Animals, University of Veterinary Medicine, Vienna, Austria.
7Oxford Autoimmune Neurology Group, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.
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