Tag: DFTD

Allorecognition in the Tasmanian devil (Sarcophilus harrisii), an endangered marsupial species with limited genetic diversity

Tasmanian devils (Sarcophilus harrisii) are on the verge of extinction due to a transmissible cancer, devil facial tumour disease (DFTD). This tumour is an allograft that is transmitted between individuals without immune recognition of the tumour cells. The mechanism to explain this lack of immune recognition and acceptance is not […]

Transmissible cancers in dogs and Tasmanian devils

The Tasmanian devil, the world’s largest marsupial carnivore, is facing possible extinction in the wild due to a transmissible facial cancer known as Tasmanian devil facial tumour disease (DFTD) (Figure 1). DFTD is spread when living cancer cells are spread between animals by biting. In DFTD, the living cancer cell […]